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Stereoselektive reduktive Dimerisierung von α‐Cyan‐β‐(4‐pyridyl)acrylsäurederivaten
Author(s) -
Kompis Ivan,
Schönholzer Peter
Publication year - 1977
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19770600234
Subject(s) - chemistry , stereoselectivity , catalysis , catalytic hydrogenation , reductive elimination , stereochemistry , acrylic acid , medicinal chemistry , organic chemistry , copolymer , polymer
Stereoselective Reductive Dimerisation of α‐Cyano‐β‐(4‐pyridyl)acrylic Acid Derivatives Catalytic hydrogenation of the α‐substituted β‐(4‐pyridyl)acrylonitriles 3 and 4 (see Scheme 3 ) yields via stereoselective reductive dimerization the substituted cyclo‐pentene derivatives 7 and 8 (see Scheme 4 and 5 ) instead of the expected dihydro‐products 5 and 6 . The mechanism of this reaction is discussed. The structure and relative configuration of 10 have been established by X‐ray single crystal analysis.