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Der massenspektrometrische Verlust von Vinylalkohol aus 1‐Amino‐3‐aryloxy‐2‐propanolen. 24. Mitteilung über das massenspektrometrische Verhalten von Stickstoffverbindungen
Author(s) -
Longoni Rita,
Berntsson Peder,
Bild Norbert,
Hesse Manfred
Publication year - 1977
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19770600113
Subject(s) - chemistry , medicinal chemistry , fragmentation (computing) , side chain , polyatomic ion , deuterium , stereochemistry , ion , organic chemistry , physics , quantum mechanics , computer science , operating system , polymer
Loss of vinyl alcohol from 1‐amino‐3‐aryloxy‐2‐propanols under electron impact Under electron impact compounds of type 1 (see Scheme 1 ) split off 44 mass units from the molecular ion. This unusual reaction was studied using derivatives and deuterium labelled compounds. It could be demonstrated that for this fragmentation reaction 16 is the important structural feature from which H 2 (C3)C(2)HOH (44 mass units) is lost. The preferred reaction mechanism involves a transition state in which four members of the side chain are involved ( Scheme 2 , mechanism 2).