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Γ‐Lakton‐ cis ‐anellierung an Δ 2 ‐ und Δ 3 ‐ Cholesten
Author(s) -
Dammann Reinhard,
Braun Manfred,
Seebach Dieter
Publication year - 1976
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19760590820
Subject(s) - chemistry , adduct , spectral line , nmr spectra database , mass spectrum , stereochemistry , medicinal chemistry , ion , organic chemistry , physics , astronomy
γ‐Lactone‐ cis ‐annulation to Δ 2 ‐ and Δ 3 ‐ Cholestene. From Δ 2 ‐ and Δ 3 ‐ cholestene the γ‐lactones 11a , 11b , 12a , and 12b are synthesized through the dibromocarbene adducts 3 and 4 , the bromohydrines 5 and 6 , the oxapiropentanes 7 and 8 , and the cyclobutanones 9a , 9b and 10a , 10b , respectively. The 13 C‐NMR.‐spectra of 1–8 and 11 as well as the ORD.‐spectra of the cyclobutanones 9 and 10 are reported.