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L'acide hydroxylamine‐O‐sulfonique, réactif de choix pour la conversion d'aldéhydes en nitriles
Author(s) -
Streith Jacques,
Fizet Christian,
Fritz Hans
Publication year - 1976
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19760590817
Subject(s) - chemistry , hydroxylamine , reagent , yield (engineering) , sulfonic acid , oxime , organic chemistry , nitrile , medicinal chemistry , metallurgy , materials science
Hydroxylamine‐O‐sulfonic acid: a convenient reagent for the conversion of aldehydes into nitriles . Hydroxylamine‐O‐sulfonic acid (HAS) proved to be an excellent reagent for the conversion of aliphatic, aromatic and heteroatomic aldehydes into nitriles. There, aldehydes in the form of suspension in HAS water solution, react rapidely to give the corresponding nitriles in high yield. Only with formylpyridines could the intermediate oxime‐O‐sulfonic acids be isolated.