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1‐aralkylated tetrahydro‐2‐benzazepines . Part II: Synthesis from 3‐(3,4‐dimethoxyphenyl)‐propylamine
Author(s) -
Berney Daniel,
Jauner Theodor
Publication year - 1976
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19760590226
Subject(s) - chemistry , benzazepines , propylamine , stereochemistry , combinatorial chemistry , organic chemistry , amine gas treating
3‐(3,4‐Dimethoxyphenyl)‐propylamine was N‐acylated with aralkanecarboxylic acid chlorides. The resulting amides were subjected to Bischler‐Napieralski ring closure to give the corresponding 1‐aralkyl‐dihydro‐2‐benzazepines. These were reduced to the title compounds.