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Eine Synthese von Vitamin A nach der Sulfonmethode
Author(s) -
Fischli Albert,
Mayer Hans,
Simon Werner,
Stoller HansJörg
Publication year - 1976
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19760590208
Subject(s) - chemistry , sulfone , allylic rearrangement , acetylation , isomerization , vitamin , retinol , chloride , organic chemistry , biochemistry , catalysis , gene
A Synthesis of Vitamin A According to the Sulfone Method. Starting from β‐ionyl phenyl sulfone 7 and an appropriate allylic chloride 10 retinol 14 has been prepared by a direct procedure. Subsequent acetylation and isomerization led to crystalline all‐ E ‐vitamin A acetate 16 .
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