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Synthesis of Vitamin A via Sulfones: A C 15 Sulfone Route
Author(s) -
Manchand P. S.,
Rosenberger M.,
Saucy G.,
Wehrli P. A.,
Wong H.,
Chambers L.,
Ferro M. P.,
Jackson W.
Publication year - 1976
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19760590207
Subject(s) - sulfone , chemistry , sulfinic acid , organic chemistry , vitamin , biochemistry
A Synthesis of vitamin A has been achieved by alkylating a β‐ionylidene‐ethyl (C 15 ) aromatic sulfone with 1‐acetoxy‐3‐chlormethyl‐2‐butene (C 5 ) followed by elimination of the corresponding sulfinic acid.