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Synthèse et configuration absolue des énantiomères du Vér apamil
Author(s) -
Ramuz Henri
Publication year - 1975
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19750580720
Subject(s) - chemistry , absolute configuration , enantiomer , verapamil , stereochemistry , organic chemistry , calcium
Synthesis and Absolute Confifguration of the Enantiomers of Verapamil . Starting from the acids IV‐(+) and IV‐(−), a synthesis of the enantiomers I‐(+) and I‐(−) of the coronary vasodilator Verapamil is described and their absolute configuration determined through a chemical filiation with the acid XII‐(S)‐(+).