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Dérivés C‐glycosyliques. XXIV . Glycosyl‐4‐thiazoles
Author(s) -
Tronchet Jean M. J.,
Eder Hansjörg
Publication year - 1975
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19750580532
Subject(s) - chemistry , thiourea , glycosyl , carbohydrate chemistry , thioacetamide , ketose , carbohydrate , medicinal chemistry , organic chemistry , aldose , glycoside , biochemistry
Abstract 4‐C‐glycosylthiazoles have been prepared by reacting thiourea or thioacetamide with a 6‐S‐benzyl‐6‐chloro‐1,2‐O‐isopropylidene‐3‐O‐methyl‐α‐D‐ xylo ‐6‐thiohexofuranos‐5‐ulose (7). The latter compound which constitutes an interesting synthetic intermediate in carbohydrate chemistry has been obtained by successive oxidation and chlorination of 6‐S‐benzyl‐1,2‐O‐isopropylidene‐3‐O‐methyl‐α‐D‐6‐thioglucofuranose.