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Beitrag zur Partialsynthese 18‐oxygenierter Cortexone II. Synthese von 18‐Oxo‐cortexon Über Steroide 231. Mitteilung
Author(s) -
Biollaz Michel,
Schmidlin Julius,
Kalvoda Jaroslav
Publication year - 1975
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19750580519
Subject(s) - chemistry , stereochemistry , medicinal chemistry
18‐Oxocortexone, a potential metabolite of 11‐deoxy‐corticosterone and precursor of aldosterone has been synthesized, starting from 3β‐hydroxy‐5‐pregnene‐20‐one acetate via subsequent functionalization at positions 18 and 21.