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Die Alkaloide von Gabunia eglandulosa S TAPF 155. Mitteilung über Alkaloide
Author(s) -
Agwada Vincent C.,
Morita Yutaka,
Renner Ulrich,
Hesse Manfred,
Schmid Hans
Publication year - 1975
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19750580405
Subject(s) - chemistry , indole test , apocynaceae , stereochemistry , bark (sound) , traditional medicine , medicine , physics , acoustics
From the root bark of the Apocynaceae Gabunia eglandulosa S TAPE seven indole alkaloids were isolated. Besides the known indole alkaloids (−)‐isovoacangine ( 1 ), (−)‐coronaridine ( 2 ), voacamine ( 3 ), vobasine ( 4 ), and perivine ( 5 ), two new bases (−)‐19‐hydroxy‐isovoacangine ( 6 ) and 19‐hydroxy‐coronaridine ( 15 ) were isolated. Compound 6 was obtained by oxidation of isovoacangine with iodine. Similar oxidation reactions with voacangine ( 12 ) were studied.