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Rationelle Synthese von α‐ L ‐Homoprolin und einiger Derivate. Herstellung von 7‐α‐ L ‐Homoprolin‐bradykinin
Author(s) -
Baláspiri L.,
Penke B.,
Papp Gy.,
Dombi Gy.,
Kov´cs K.
Publication year - 1975
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19750580402
Subject(s) - chemistry , bradykinin , stereochemistry , biochemistry , receptor
Abstract Optically pure α‐ L ‐homoproline can be prepared with good yield from N‐bnezyloxycarbonyl‐ L ‐proline through its diazoketone‐derivative. Preparation of derivatives of α‐ L ‐homoproline used in peptide chemistry, and of 7‐α‐ L ‐homoproline‐bradykinin, as well as biological investigation of the latter are described.