Premium
Zur Verwendung des Tosylaminocarbonyl‐Restes als Amino‐Schutzgruppe in der Peptidchemie
Author(s) -
Künzi Hans,
Studer Rolf O.
Publication year - 1975
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19750580119
Subject(s) - chemistry , tripeptide , amino acid , group (periodic table) , peptide , stereochemistry , biochemistry , organic chemistry
Several N‐tosylaminocarbonyl amino acids and corresponding di‐ and tripeptides were prepared in order to investigate the suitability of the tosylaminocarbonyl group as an amino protecting group in peptide chemistry. The group is shown to be selectively cleavable under neutral conditions.