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The Crystal Structure of the NaNCS Complex of Nonactin
Author(s) -
Dobler Max,
Phizackerley Richard Paul
Publication year - 1974
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19740570319
Subject(s) - chemistry , ionophore , crystal structure , oxygen atom , ligand (biochemistry) , crystallography , equidistant , ether , oxygen , membrane , stereochemistry , molecule , receptor , organic chemistry , biochemistry , geometry , mathematics
The NaNCS complex of the macrotetrolide antibiotic nonactin, which acts as an ionophore with biological and artificial membranes crystallizes in the space group C2/c, a = 15.55, b = 19.59, c = 15.31 Å, β = 90°. The X‐ray crystal structure investigation shows that Na + is coordinated by four carbonyl oxygen atoms (Na + … O, 2.42 Å) and four ether oxygen atoms (Na + … O, 2.77 Å). The cubic coordination by eight equidistant oxygen atoms observed in the K + complex (K + … O, 2.81 Å) is thus deformed. This, however, requires only very small changes in the ligand conformation.