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Structure of a boron‐free hydrolysis product from Boromycin
Author(s) -
Marsh Wayne,
Dunitz Jack D.,
White David N. J.
Publication year - 1974
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19740570103
Subject(s) - chemistry , boron , hydrolysis , molecule , valine , stereochemistry , product (mathematics) , crystallography , organic chemistry , amino acid , biochemistry , geometry , mathematics
The structure of des ‐boron‐ des ‐valine‐boromycin C 40 H 68 O 14 · H 2 O (DBDVB), the product obtained by hydrolysis of the antibiotic boromycin C 45 H 74 BNO 15 , has been determined by X‐ray analysis. The molecule is remarkably similar in constitution, configuration and even in conformation to those of boromycin and des ‐valine‐boromycin determined previously [2], showing that the overall molecular shape is retained on removal of the spiro boron atom.