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Ansamycine, eine neuartige Klasse von mikrobiellen Stoffwechselprodukten
Author(s) -
Prelog Vladimir,
Oppolzer Wolfgang
Publication year - 1973
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19730560716
Subject(s) - geldanamycin , chemistry , biogenesis , stereochemistry , computational biology , biochemistry , gene , biology , hsp90 , heat shock protein
Isolation, structure elucidation, and biological properties of a novel class of microbial metabolites, ansamycins, are reviewed as background for the following papers. Structural similarities and differences of ansamycins (rifamycins, tolypomycin, streptovaricins, and geldanamycin) relevant to the common steps in their biogenesis are discussed.