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Stereoselektive Bildung der C‐C‐Bindung in der Kopplungsreaktion zwischen sek. Alkylmagnesiumbromiden und ungesättigten Halogeniden: Asymmetrische Induktion durch einen optisch aktiven Diphosphin‐Nickel‐Komplex
Author(s) -
Consiglio Giambattista,
Botteghi Carlo
Publication year - 1973
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19730560137
Subject(s) - chemistry , reagent , isomerization , optically active , nickel , halide , grignard reagent , stereochemistry , medicinal chemistry , catalysis , organic chemistry
The catalyzed cross‐coupling reaction of secondary racemic Grignard reagents with unsaturated halides takes place stereospecifically in the presence of the nickel chiral complex 4 although some isomerisation is occurring this reaction can be useful to prepare optically active hydrocarbons.