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Über die Synthese der Pilocarpus ‐Alkaloide Isopilosin und Pilocarpin, sowie die absolute Konfiguration des (+)‐Isopilosins
Author(s) -
Link H.,
Bernauer Karl
Publication year - 1972
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19720550402
Subject(s) - chemistry , stereochemistry
A novel synthesis for rac ‐pilosinine ( 6 rac ) and transformation of (+)‐pilosinine ( 6 ) into the pilocarpus alkaloids (+)‐isopilosine ( 9 ) and (+)‐pilocarpine ( 18 ) are described. By correlation via 5 with 18 the absolute configuration of (+)‐isopilosine ( 9 ) is established.