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The Reaction of Phenyl(trichloromethyl)mercury with Substituted Norbornenes
Author(s) -
Jefford C. W.,
Hill D. T.,
Goré J.,
Waegell B.
Publication year - 1972
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19720550307
Subject(s) - chemistry , steric effects , mercury (programming language) , medicinal chemistry , double bond , reactivity (psychology) , bicyclic molecule , organic chemistry , computer science , programming language , medicine , alternative medicine , pathology
The addition of phenyl(trichloromethyl)mercury to five substituted norbornenes is described, and the results compared with those obtained with bicyclo[2.2.2]oct‐2‐ene and 3,3,5,5‐tetramethylcyclopentene. The reaction proves to be useful for synthetic purposes, in that it leads usually to ring expansion. However, a possible disadvantage is that the addition step is sensitive to steric hindrance and depends on the reactivity of the double bond.