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Reaktionen von Steroid‐Hypojoditen X. Fragmentierung von 20‐Hydroxy‐Steroiden (17‐Jod‐androstane). Über Steroide, 226. Mitteilung
Author(s) -
Biollaz M.,
Kalvoda J.
Publication year - 1972
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19720550206
Subject(s) - chemistry , androstane , stereochemistry , steroid , hormone , biochemistry
In the hypoiodite reaction of 20‐hydroxy steroids, 17α‐ and 17β‐iodo androstanes are formed as by‐products by fragmentation of the intermediate alkoxy radicals. The epimeric iodides show antipodal CD.‐ and ORD.‐ curves in accordance with their absolute configuration at the relevant chiral centre C(17).