Steroide und Sexualhormone 242. Mitteilung [1] herstellung von 14β‐hydroxy‐20‐keto‐δ 16 ‐steroiden: Ein neuer ergiebiger zugang zu 3‐O‐methyl‐17α, 20ξ‐tetrahydrobatrachotoxinin A | Zendy

Gössinger Frl. E. | Zendy; Graf W. | Zendy; Imhof R. | Zendy; Wehrli H. | Zendy

Premium

Steroide und Sexualhormone 242. Mitteilung [1] herstellung von 14β‐hydroxy‐20‐keto‐δ 16 ‐steroiden: Ein neuer ergiebiger zugang zu 3‐O‐methyl‐17α, 20ξ‐tetrahydrobatrachotoxinin A

Author(s) -

Gössinger Frl. E.,

Graf W.,

Imhof R.,

Wehrli H.

Publication year - 1971

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19710540844

Subject(s) - chemistry , epoxide , yield (engineering) , stereochemistry , medicinal chemistry , organic chemistry , catalysis , materials science , metallurgy

A novel method for the reductive epoxide opening in a 14β, 15β‐epoxy‐20‐oxo‐Δ 16 ‐pregnene 4 affords an almost quantitative yield of the 14β‐hydroxy‐20‐oxo‐Δ 16 ‐pregnene 5. This leads to a considerable improvement of the formerly published synthesis of 3‐O‐methyl 17 α, 20ξ‐tetrahydrobatrachotoxinin A ( 2 ) [3].

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research