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Eine neue Synthese von 3,6‐Dialkyl‐1,2,4,5‐tetrazinen
Author(s) -
Skorianetz W.,
Sz. Kováts E.
Publication year - 1971
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19710540721
Subject(s) - chemistry , alkyl , hydrazine (antidepressant) , medicinal chemistry , organic chemistry , chromatography
A new synthesis of 3,6‐dialkyl‐1,2,4,5‐tetrazines (or ‐ s ‐tetrazines), 4 , is described (see reaction scheme [1→2→3→4]). The 3,6‐dialkyl‐hexahydro‐ s ‐tetrazines, 2 , R = n ‐alkyl, are readily available by the reaction of fatty aldehydes and hydrazine. s ‐Tetrazines with branched substituents and mixed alkyl‐ s ‐tetrazines can also be prepared by the same procedure, however, in lower yields.