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Die Komplexbildung der neutralen Amidgruppe mit Cu 2+ in wässeriger Lösung
Author(s) -
Kaden Th.,
Zuberbühler A.
Publication year - 1971
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19710540516
Subject(s) - chemistry , ethylenediamine , amide , chelation , stability constants of complexes , ligand (biochemistry) , medicinal chemistry , glycine , complex formation , stereochemistry , inorganic chemistry , aqueous solution , organic chemistry , receptor , amino acid , biochemistry
The interaction between Cu 2+ and the terdentate ligands N‐picolinoyl‐ethylenediamine, glycine‐2‐pyridylmethylamide, N α ‐(2‐pyridylmethyl)‐glycinamide and N α ‐(2‐pyridylmethyl)‐glycine‐ethylamide, respectively, has been studied by spectrophotometry and potentiometry. At high pH values the ionised amide group undergoes complex formation and the resulting chelates have similar structures and stabilities. In slightly acidic solution however, each ligand gives rise to a different species. These facts are explained by assuming that the neutral amide group coordinates through its carbonyl oxygen atom. The stability constant and the absorption spectrum of each complex have been calculated by computer programmes.