Premium
Neuartige massenspektrometrische Zerfallsreaktionen bei α,ω‐disubstituierten Alkanen. 15. Mitteilung über das massenspektrometrische verhalten von stickstoffverbindungen [1]
Author(s) -
Veith H. J.,
Guggisberg A.,
Hesse M.
Publication year - 1971
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19710540224
Subject(s) - chemistry , fragmentation (computing) , substituent , ion , medicinal chemistry , mass spectrum , nitrogen atom , nitrogen , stereochemistry , organic chemistry , group (periodic table) , computer science , operating system
Abstract The mass spectral behaviour of α,ω‐disubstituted alkanes and, especially, that of different N‐substituted α,ω‐diaminoalkanes has been investigated. It was found that the two amino groups which are separated by CH 2 ‐groups can fragment only to a small extent indepently from each other. Yet those fragmentation reactions are predominant in which both functional groups participate. The main reactions of this type are: 1 Loss of the N‐substituent (R) from the molecular ion, leading to the [ M + —R]‐ions. 2 Loss of NH 3 , primary or secondary amines from the [ M + —R]‐ion in the case of monodi‐, tri‐ and tetra‐substituted diamino compounds respectively. 3 α‐Cleavage to the non charged nitrogen atom by forming the ions4 S Ni ‐type fragmentation.The mechanisms of these fragmentation patterns were deduced by using D‐labelled derivatives, from metastabile peaks and high resolution mass spectrometry. These reactions seem to be typical for disubstituted alkanes.