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An Efficient Synthesis of Thyrotropin Releasing Hormone (TRH)
Author(s) -
Rivaille Pierre,
Milhaud Gérard
Publication year - 1971
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19710540139
Subject(s) - chemistry , thyrotropin releasing hormone , tripeptide , hormone , combinatorial chemistry , stereochemistry , medicine , peptide , biochemistry
A convenient and simple synthesis of L ‐pyroglutamyl‐ L ‐histidyl‐ L ‐prolinamide is described. Two pathways using the solid phase technique have led to the pure tripeptide.