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Über die Reaktion von Schwefel mit Aminen und Formaldehyd. Eine neue Methode zur Herstellung von Thioformamiden und Dithiocarbamaten
Author(s) -
Maier Ludwig
Publication year - 1970
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19700530541
Subject(s) - chemistry , formaldehyde , medicinal chemistry , organic chemistry
The reaction of sulfur with primary or secondary amines and formaldehyde has been studied. A simple one step process for the preparation of thioformamides (RR′NCHS; R H, R′ CH 3 , C 2 H 5 ; R R′ CH 3 , C 2 H 5 ; R+R′ (CH 2 ) 4 −, (CH 2 ) 5 −, C 2 H 4 OC 2 H 4 −) and the amine salts of N, N‐dialkyl‐dithiocarbamic acids (R 2 NCS 2 · H 2 NR 2 , R CH 3 , C 2 H 5 , C 4 H 9 ; R 2 (CH 2 ) 4 −, (CH 2 ) 5 −, C 2 H 4 OC 2 H 4 −) is reported. In addition, the isolation of diethylamidosulfoxylic acid, (C 2 H 5 ) 2 NSOH · 1/2 H 2 O, the first derivative of a new class of compounds, is described. The physical properties and the 1 H‐NMR. spectra of the above mentioned compounds are given.