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New Methods for the Synthesis of Oxygenated Carotenoids
Author(s) -
Surmatis J. D.,
Walser A.,
Gibas J.,
Schwieter U.,
Thommen R.
Publication year - 1970
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19700530513
Subject(s) - canthaxanthin , chemistry , carotenoid , zeaxanthin , condensation , decarboxylation , xanthophyll , organic chemistry , vitamin , lutein , biochemistry , astaxanthin , catalysis , physics , thermodynamics
Six keto carotenoids ( 4 , 5 , 6 , 11 , 12 , and 22 ) were synthesized from intermediates which were prepared from the condensation products of mesityl oxide and acetoacetic ester. Compounds 4 and 22 can serve as precursors for zeaxanthin, while 5 can be used as an intermediate for xanthophyll. Echinenone and canthaxanthin were prepared by a new approach from vitamin A. Two new types of keto carotenoids with the keto functions incorporated into the unsaturated chain were prepared.