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Dérivés propargyliques IX [1] Propargyl‐pyrrolidinols et propargyl‐perhydro‐azépinols et leurs esters
Author(s) -
Prost M.,
Urbain M.,
Charlier R.
Publication year - 1969
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19690520428
Subject(s) - chemistry , propargyl , respiration , stereochemistry , medicinal chemistry , organic chemistry , catalysis , botany , biology
The authors describe the synthesis of 3‐propargyl‐pyrrolidin‐3‐ols and 4‐propargylperhydro‐azepin‐4‐ols, and their esters. The antitussive, analgetic, and local anesthetic activities as well as the respiration stimulative effect of these compounds are related.