Rac.  cis ‐ und  trans ‐ 1, 2‐Dimethyl‐4‐hydroxy‐6, 7‐dimethoxy‐1, 2, 3, 4‐tetrahydro‐isochinolin, Synthese und Stereochemie | Zendy

Grethe G. | Zendy; Uskokovice M. | Zendy; Williams T. | Zendy; Brossi A. | Zendy

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Rac. cis ‐ und trans ‐ 1, 2‐Dimethyl‐4‐hydroxy‐6, 7‐dimethoxy‐1, 2, 3, 4‐tetrahydro‐isochinolin, Synthese und Stereochemie

Author(s) -

Grethe G.,

Uskokovice M.,

Williams T.,

Brossi A.

Publication year - 1967

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19670500826

Subject(s) - chemistry , isoquinoline , stereochemistry , nmr spectra database , medicinal chemistry , spectral line , physics , astronomy

The synthesis of rac. cis ‐ and trans ‐1,2‐dimethyl‐4‐hydroxy‐6,7‐dimethoxy‐1,2,3,4‐tetrahydro‐isoquinoline (respectively 8 and 9 ) is described. The relative configuration of these amino alcohols was determined by a detailed analysis of nmr.‐ and ir.‐spectra. The comparison of the nmr.‐spectra of 8 and 9 with that of gigantine reveals the non identity of these compounds.

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