Zur Synthese des Ecdysons. IV. Mitteilung über Insektenhormone . Die Synthese des natürlichen Häutungshormons | Zendy

Kerb U. | Zendy; Schulz G. | Zendy; Hocks P. | Zendy; Wiechert R. | Zendy; Furlenmeier A. | Zendy; Fürst A. | Zendy; Langemann A. | Zendy; Waldvogel G. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Zur Synthese des Ecdysons. IV. Mitteilung über Insektenhormone . Die Synthese des natürlichen Häutungshormons

Author(s) -

Kerb U.,

Schulz G.,

Hocks P.,

Wiechert R.,

Furlenmeier A.,

Fürst A.,

Langemann A.,

Waldvogel G.

Publication year - 1966

Publication title -

helvetica chimica acta

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.74

H-Index - 82

eISSN - 1522-2675

pISSN - 0018-019X

DOI - 10.1002/hlca.19660490519

Subject(s) - chemistry , hydroxylation , stereochemistry , tetrahydropyran , ecdysone , ether , metalation , ring (chemistry) , organic chemistry , hormone , enzyme , biochemistry

Ecdysone ( 9 ), a hormone responsible for the skin shedding process of arthropoda , has been synthesized. (20 S )‐2β,3β‐Diacetoxy‐20‐formyl‐5β‐pregn‐7‐en‐6‐one was prepared from the corresponding carboxylic acid and converted into ecdysone by a G RIGNARD reaction with 2‐methyl‐3‐butyn‐2‐ol tetrahydropyran‐2‐yl ether, followed by hydrogenation of the triple bond, removal of the protecting groups, and hydroxylation in the 14α‐position. C‐22‐isoecdysone was obtained as a by‐product.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research