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Synthèse d'amino‐oxadiazoles ‐ 1, 2, 4
Author(s) -
Eloy F.,
Lenaers R.
Publication year - 1966
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19660490428
Subject(s) - chemistry , guanidine , hydrazine (antidepressant) , primary (astronomy) , chloride , hydrochloride , combinatorial chemistry , organic chemistry , medicinal chemistry , biochemistry , physics , astronomy
Two new syntheses of 5‐amino‐1,2,4‐oxadiazoles are described. The first one is based on the reaction of guanidine on benzhydroxamyl chloride. The second is more general and consists in allowing primary or secondary amines, hydrazine or guanidine to react with 5‐trichloromethyloxadiazoles.