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Sur la réaction de l'acide β‐mercaptopropionique, du β‐diéthylamino‐éthylmercaptan et de la cystéine avec divers isothiocyanates
Author(s) -
Cherbuliez Emile,
Buchs A.,
Marszalek J.,
Rabinowitz J.
Publication year - 1965
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19650480622
Subject(s) - chemistry , aryl , medicinal chemistry , yield (engineering) , stereochemistry , organic chemistry , alkyl , materials science , metallurgy
By treating β‐mercaptopropionic acid with aryl (aralkyl) isothiocyanates in weak alkaline medium, the authors have obtained the corresponding β‐(N‐aryl(aralkyl)‐thiocarbamoylthio)‐propionic acids which, heated 2 hours at 120°, yield the corresponding 3‐aryl(aralkyl)‐4‐oxo‐2‐thiono‐tetrahydrothiazines.