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Synthese von All‐ D ‐Val 5 ‐Angiotensin II‐Asp 1 ‐β‐Amid
Author(s) -
Vogler K.,
Studer R. O.,
Lergier W.,
Lanz P.
Publication year - 1965
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19650480621
Subject(s) - chemistry , angiotensin ii , amide , stereochemistry , receptor , biochemistry
The synthesis of all‐ D ‐Val 5 ‐Angiotensin II‐Asp 1 ‐β‐Amide (Scheme 2), the antipode of the active principle of Hypertensin CIBA®, is carried out according to known schemes in the L ‐series. It showed neither inhibitory nor angiotensin‐like effects up to concentrations of 10 −3 .