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Synthesen in der Polymyxinreihe. 10. Mitteilung . Die Synthese von Colistin A (Polymyxin E 1 )
Author(s) -
Studer R. O.,
Lergier W.,
Lanz P.,
Böhni Erika,
Vogler K.
Publication year - 1965
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19650480617
Subject(s) - chemistry , colistin , polymyxin b , polymyxin , antibiotics , stereochemistry , biochemistry
Colistin A (Polymyxin E 1 ), an antibiotic isolated in 1950 from cultures of B. colistinus , is shown by synthesis to have the cyclo‐heptapeptide structure VI (Figure 1) already proposed by other workers on the evidence of degradation studies.