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Synthesen in der Polymyxin‐Reihe 9. Mitteilung . Synthese von Polymyxin B 1
Author(s) -
Vogler K.,
Studer R. O.,
Lanz P.,
Lergier W.,
Böhni E.
Publication year - 1965
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19650480523
Subject(s) - chemistry , stereochemistry , polymyxin , polymyxin b , antibiotics , biochemistry
The synthesis of the cycloheptapeptide 7α (Fig. 4) containing the α,γ‐diaminobutyric acid residues only in the L form, and its cristallization as pentaphosphate are reported. This latter substance proved to be in all respects identical with the cristalline penta‐ phosphate of natural polymyxine B 1 .