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Metallionen‐Katalyse bei der H 2 O 2 ‐ bzw. Radikalbildung durch autoxydable Cytostatica
Author(s) -
Erlenmeyer H.,
Zell R.,
Brintzinger H.,
Prijs B.
Publication year - 1964
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19640470314
Subject(s) - chemistry , methylhydrazine , metal ions in aqueous solution , medicinal chemistry , metal , stereochemistry , organic chemistry , phenylhydrazine
The formation of H 2 O 2 during autoxydation of certain cytostatic agents like α‐aminoketones and methylhydrazine derivatives is shown to depend on the presence of metal ions. The biochemical implications of this finding, e.g. for the development of cytostatic tumor therapy and of appropriate tests are discussed.