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Selektive Reduktions‐ und Oxydationsreaktionen an lysergsäure‐ Derivaten. 2.3‐Dihydro‐ und 12‐Hydroxy‐lysergsäureamide. 59. Mitteilung über Mutterkornalkaloide
Author(s) -
Stadler P. A.,
Frey A. J.,
Troxler F.,
Hofmann A.
Publication year - 1964
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19640470309
Subject(s) - chemistry , lysergic acid , dehydrogenation , stereochemistry , nitroso , medicinal chemistry , organic chemistry , catalysis
A stereoselective reduction of d ‐lysergic acid amides to the 2,3‐dihydro derivatives is described. These new dihydro‐compounds can be dehydrogenated and oxidised with potassium nitroso‐disulphonate to form the corresponding 12‐hydrosy‐ d ‐lysergic acid amides besides the corresponding d ‐lysergic acid amides.