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Sur la saramycétine (= X‐5079 C), polypeptide antibiotique de Streptomyces saraceticus . I. Premières données concernant sa structure
Author(s) -
Baudet P.,
Cherbuliez E.
Publication year - 1964
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19640470233
Subject(s) - chemistry , cystine , hydrochloric acid , hydrolysis , sulfur , yield (engineering) , stereochemistry , organic chemistry , enzyme , cysteine , materials science , metallurgy
Hydrolysis by strong hydrochloric acid degrades the antibiotic Saramycetin (= X‐5079 C), discovered by B ERGER et al . [l], with production of different sulphur‐free amino acids and of two types of sulphur containing compounds: (a) large amounts of cystine (23 mol. for a molecular weight of 14000 for saramycetin) originated from at least 46 cysteinogenetic groups which are shown to be probably thiazolidinic;(b) acids containing heterocyclic sulphur, for which the name of saramycetic acids is proposed and which do not yield cystine by hydrolysis.