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Über die Aktivierung des Biotins
Author(s) -
Valloton M.,
Leuthardt F.
Publication year - 1964
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19640470140
Subject(s) - biotin , chemistry , hydroxylamine , adenylate kinase , biochemistry , enzyme
Biotin hydroxamate is formed when [ 14 C]‐biotin is incubated with a partially purified extract of chicken liver in the presence of ATP, Mg ++ and an excess of hydroxylamine. Free biotin and the hydroxamate have been separated by chromato‐ graphy on anion‐exchange paper. Hence we conclude that biotin was activated to form biotin‐adenylate.