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Desoxypodophyllinsäure‐1 β‐D‐glucopyranosyl‐ester, ein neues. Lignanderivat aus Podophyllum peltatum L. und P. emodi W ALL . 13. Mitteilung über mitosehemmende Naturstoffe
Author(s) -
Kuhn Max,
von Wartburg A.
Publication year - 1963
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19630460632
Subject(s) - chemistry , lignan , rhizome , podophyllum , stereochemistry , traditional medicine , medicine , podophyllotoxin
The isolation of lignan J, C 28 H 34 O 13 , a new compound from the roots and rhizomes of American Podophyllum peltatum L. and Indian P. emodi Wall. is described. Lignan J is easily cleaved to desoxypodphyllotoxin and D‐glucose. By degradation of its penta‐phenylurethane, the structure of lignan J has been deduced as the 1β‐D‐glucopyranosylester of desoxypodophyllinic acid. It is suggested that glucose esters of this type may act as intermediates in the biogenesis of lignans.