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Synthèse de la Sér 4 ‐oxytocine, de l'Ala 4 ‐oxytocine, de la Sér 5 ‐oxytocine et de l'Ala 5 ‐oxytocine
Author(s) -
Guttmann St.,
Boissonnas R. A.
Publication year - 1963
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19630460517
Subject(s) - oxytocin , chemistry , stereochemistry , medicine
Ser 4 ‐oxytocin and Ala 4 ‐oxytocin have been synthesized and found to possess biological properties not very different from those of isotocin. Ser 5 ‐oxytocin and Ala 5 ‐oxytocin have also been prepared and found to be almost inactive. An hypothesis concerning the mode of fixation of oxytocin on its receptor is presented.