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Über den Einbau des Kohlenstoffs der Glucose in die Harnsäure bei Drosophila melanogaster . Vorläufige Mitteilung
Author(s) -
BrennerHolzach O.,
Leuthardt F.
Publication year - 1963
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19630460438
Subject(s) - chemistry , purine , glyceric acid , drosophila melanogaster , uric acid , stereochemistry , biochemistry , enzyme , catalysis , gene
1. Uric acid was isolated from larvae of Drosophda melanogaster to which glucose‐[1‐ 14 C] and glu∼ose‐[6‐ 14 C] had been fed. The specific activity of the atoms 2 and 8 of the purine skeleton was considerably higher after feeding glucose‐ [6–14C] than after glucose‐ [1‐ 14 C]. The activated formate used in building the purine ring probably derives from the C 3 of glyceric acid (glycerate → hydroxypyruvate → serine).