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Synthèse de la Dé‐Pro 7 ‐oxytocine, de la Dé‐Leu 8 ‐oxytocine et de la Dé‐Gly 9 ‐oxytocine
Author(s) -
Jaquenoud P.A.,
Boissonnas R. A.
Publication year - 1962
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19620450511
Subject(s) - oxytocin , chemistry , stereochemistry , amino acid , biochemistry , medicine
Three new analogues of Oxytocin in which one of the amino‐acids of the peptidic side‐chain has been omitted, i.e. De‐Pro 7 ‐Oxytocin, De‐Leu 8 ‐Oxytocin and De‐Gly 9 ‐Oxytocin, have been synthesized according to the scheme (3+5). All three analogues exhibit about 1% of the uterus contracting and milk ejecting activities of Oxytocin, but no avian depressor property.