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Synthese des Bradykininanalogen mit umgekehrter Aminosäuresequenz
Author(s) -
Vogler K.,
Lanz P.,
Lergier W.
Publication year - 1962
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19620450219
Subject(s) - chemistry , bradykinin , stereochemistry , peptide , amino acid , sequence (biology) , peptide synthesis , biochemistry , receptor
The nonapeptide H‐Arg‐Phe‐Pro‐Ser‐Phe‐Gly‐Pro‐Pro‐Arg‐OH with the reversed amino acid sequence of bradykinin has been synthesized according to the scheme outlined above. This peptide exerted no bradykinin activity at concentrations up to 10 −5 .