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Synthese von Dab 1 ‐Dab 9 ‐Bradykinin
Author(s) -
Vogler K.,
Studer R. O.,
Lergier W.
Publication year - 1961
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19610440607
Subject(s) - bradykinin , chemistry , chymotrypsin , carboxypeptidase , stereochemistry , enzyme , biochemistry , receptor , trypsin
Dab 1 ‐Dab 9 ‐bradykinin (Dab‐Pro‐Pro‐Gly‐Phe‐Ser‐Pro‐Phe‐Dab) has been prepared by a new procedure which differs from known syntheses of bradykinin. Against carboxypeptidase and chymotrypsin this synthetic analogue of bradykinin behaves in a way similar to that of the natural hormone, but it does not exhibit any pharmacological activity on the isolated rat uterus.