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Amidchloride als elektrophile Reagentien: Umsatz mit Methiden (Cyaninbildung) und Alkoholaten
Author(s) -
Bosshard H. H.,
Jenny E.,
Zollinger Hch.
Publication year - 1961
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19610440504
Subject(s) - chemistry , aldehyde , hydrolysis , cyanine , dimethylformamide , chloride , amide , organic chemistry , alkaline hydrolysis , medicinal chemistry , catalysis , physics , quantum mechanics , solvent , fluorescence
1. The reaction of dimethylformamide chloride with N‐methylbenzothiazolone methide yields the hemicyanine 2‐dimethylaminovinyl‐3‐methyl‐benzothiazolium chloride. By alkaline hydrolysis of the hemicyanine, the vinylogous aldehyde is obtained. The hemicyanine forms the symmetric cyanine (Thiazole Purple) by reaction with a second molecule of the methide. The cyanine as well as the vinylogous aldehyde can also be obtained directly from the amide chloride by reaction with the methide.