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Verwendung farbiger Schutzgruppen zur Synthese von bis‐homo‐Gramicidin S
Author(s) -
Schwyzer R.,
Sieber P.
Publication year - 1960
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19600430704
Subject(s) - chemistry , gramicidin , stereochemistry , gramicidin s , lysine , amino acid , biochemistry , membrane
An improved synthesis of bis ‐ homo ‐gramicidin S is described, using the p‐(p′‐methoxyphenylazo)‐benzyloxycarbonyl (MZ) group for intermediary protection of the ϵ‐amino group of lysine. Partial dinitrophenylation was used to determine the molecular weight of the compound.