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Benzimidazol‐Derivate und verwandte Heterocyclen. IV. Die Kondensation von o‐Phenylendiamin mit α‐Aryl‐ und γ‐Aryl‐acetessigester
Author(s) -
Rossi A.,
Hunger A.,
Kebrle J.,
Hoffmann K.
Publication year - 1960
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19600430413
Subject(s) - chemistry , benzimidazole , medicinal chemistry , aryl , organic chemistry , alkyl
The reaction of o‐phenylenediamine with α‐phenyl‐ and γ‐phenyl‐acetoacetic ester has been investigated. The former yields mainly 1‐β‐methylstyryl‐benzimidazole‐2‐one (IX), the latter affords 4,7‐dihydro‐5‐benzyl‐1 H ‐2,3‐benzo‐1,4‐diazepin‐7‐one (XVI). The structures of these products have been elucidated.