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Zur Synthese von N‐t‐Butyloxycarbonyl‐aminosäuren
Author(s) -
Schwyzer R.,
Sieber P.,
Kappeler H.
Publication year - 1959
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19590420734
Subject(s) - chemistry , azide , reagent , combinatorial chemistry , stereochemistry , protecting group , organic chemistry , alkyl
The introduction of the t‐butyloxycarbonyl protecting group into amino‐acids by a new method, using the stable t‐butyloxycarbonyl azide (III), is described. Over previous methods the new procedure offers obvious advantages owing to the stability of the reagent and the resulting good yields.