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Synthese von Ubichinon(45) und Ubichinon(50)
Author(s) -
Rüegg R.,
Gloor U.,
Goel R. N.,
Ryser G.,
Wiss O.,
Isler O.
Publication year - 1959
Publication title -
helvetica chimica acta
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.74
H-Index - 82
eISSN - 1522-2675
pISSN - 0018-019X
DOI - 10.1002/hlca.19590420733
Subject(s) - chemistry , hydroquinone , isoprene , quinone , stereochemistry , organic chemistry , copolymer , polymer
Ubiquinone(45) has been synthesized from 5‐methyl‐2, 3‐dimethoxy‐hydroquinone and solanesol, which is a C 45 isoprenoid alcohol. Chain‐lengthening of solanesol by one isoprene unit and condensation with 5‐methyl‐2, 3‐dimethoxy‐hydroquinone led to ubiquinone(50). The synthetic ubiquinone(45) proved to be identical with a natural sample from liver of vitamin A deficient rats and synthetic ubiquinone‐(50) with a natural sample from pig heart.
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